Head injuries almost double a person's risk of developing dementia, new research shows. Experts say the study by University of Maryland neurologists could transform how brain inflammation is understood, and, ultimately, how it is treated. It showed inflammation caused by traumatic brain injury can spread and cause long-lasting damage. The risk is particularly high for men aged between 41 and 56, they found.
A growing swell of research has shown that chronic inflammation leads to progressive cell loss after traumatic brain injury (TBI). Some studies have shown that neuroinflammation often can continue for years after TBI, causing severe brain damage. However, few researchers have been able to pinpoint how this inflammatory process unravels, and how it could be curbed. To investigate the lingering impact of inflammation, a team led by Dr Alan Faden focused on microparticles produced by inflammatory brain cells.
These microparticles can activate normal immune cells, making them potentially toxic to brain neurons.
They are released from cells known as microglia, immune cells that are common in the brain.
Read more: http://www.dailymail.co.uk/health/article-4676478/Head-injuries-nearly-DOUBLE-risk-dementia.html#ixzz4mFa6ninS